ANNOUNCEMENT

“Immunodeficiencies and Autoimmune Diseases”

A Scientific Colloquium

November 13-15, 2009

Intercontinental Harbor Court Hotel, Baltimore, MD

Presented by

American Autoimmune Related Diseases Association (AARDA)

and co-presented by

Johns Hopkins University Center for Autoimmune Disease Research and the Immune Deficiency Foundation (IDF)

Call for Abstracts: For Information on abstract submission, click this link: www.aarda.org/user_content/Immunodef_AbstractCall.php

Colloquium is sponsored by generous grants from the following corporations:  

About the Colloquium:

The Colloquium is a three-day meeting bringing together scientific investigators from diverse backgrounds and interest for discussion and conversation.  Featuring a multidisciplinary approach, the meeting will address the relationship between immunodeficiencies and autoimmune diseases through the following:

 ·        Focus on the specific mechanisms by which immune dysregulation, both over and under, that might relate to the development of autoimmune disease and treatment failure.

·        Identify new opportunities to study genetic mechanisms that help to explain the connection between immune deficiencies in autoimmune disease.

·        Discuss research strategies to initiate collaborative research in the area of immunoregulation in autoimmune diseases and immunodeficiency.

·        Adopt a multidisciplinary approach in meeting specific aims by bringing together specialists from many disciplines, including but not limited to immunologists, infectious disease specialists, and rheumatologists.

·        Select critical research areas that represent unmet needs or are presently under-explored.

Colloquium Program Agenda:

 Friday, November 13, 2009

5:00 p.m. to 9:00 p.m.          Registration  

6:00 p.m. to 9:00 p.m.          Welcome Dinner and Keynote Presentation

·        Welcome by Noel R. Rose, M.D., Ph.D., Johns Hopkins University

·        Keynote Address presented by Max Cooper, M.D., Emory University: “An Evolutionary View of   Immunodeficiencies and Autoimmune Diseases”

Saturday, November 14, 2009

7:00 a.m. to 7:30 a.m.          Continental Breakfast            

Session I                               Panel Discussion: “Significant Clinical Features”

7:30 a.m. to 7:45 a.m.        Introduction        

Chair: Josiah Wedgwood, M.D., Ph.D.

Clinical Immunology, National Institute of Allergy and Infectious Diseases/National Institutes of Health (NIH)

7:45 a.m. to 8:10 a.m.          Autoimmune Diseases    

Betty Diamond, M.D.

Center Head, Department of Autoimmune Diseases,

The Feinstein Institute for Medical Research 

8:10 a.m. to 8:35 a.m.          Immunodeficiency Disease        

R. Michael Blaese, M.D., Medical Director,

Immune Deficiency Foundation (IDF)

8:35 a.m. to 9:00 a.m.          Provocateur Discussant 

Warren Strober, M.D.

Senior Investigator, Chief, Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases/National Institutes of Health (NIH)

Session II                              “Lessons from Monogenic Disorders”

9:00 a.m. to 9:15 a.m.          Introduction

H. W. Schroeder, Jr., M.D., Ph.D., Professor of Medicine, Microbiology and Genetics, University of Alabama at Birmingham.

9:15 a.m. to 9:40 a.m.          ALPS

Thomas Fleisher, M.D., Chief, Department of Laboratory Medicine, Chief, Immunology Services, DLM, National Institutes of Health (NIH) Clinical Center

9:40 a.m. to 10:15 a.m.        IPEX  

Troy Torgerson, M.D., Ph.D., Co-Director of the Immunodeficiency Molecular Diagnostics Laboratory, Seattle Children’s Research Institute

10:15 a.m. to 10:25 a.m.      Provocateur Discussant 

Hans Ochs, M.D., Professor of Pediatrics

Jeffrey Modell Chair of Pediatric Immunology Research Center for Immunity and Immunotherapy,

Seattle Children's Research Institute

University of Washington

10:25 a.m. to 10:55 a.m.      Break   

Session III                            “Lessons from the B Cell”

10:55 a.m. to 11:10 a.m.      Introduction

Melvin Berger, M.D., Ph.D.

Division Chief, Allergy and Immunology, University Hospitals of Cleveland; Professor, Case Western Reserve University

11:10 a.m. to 11:35 a.m.      BAFF

Susan L. Kalled, Ph.D., Biogen Idec

11:35 a.m. to 12:00 p.m.      B Cell Tolerance    

Eric Meffre, Ph.D., Associate Professor of Immunology, Yale University

12:00 p.m. to 12:15 p.m.      Provocateur Discussant 

Paolo Casali, M.D., Ph.D.

Donald L. Bren Professor of Medicine, Molecular Biology & Biochemistry, School of Medicine; Director, Institute for Immunology, University of California, Irvine

12:15 p.m. to 1:25 p.m.        Lunch   

Session IV                           “Lessons from the Complement System”

1:25 p.m. to 1:40 p.m.          Introduction

J. P. Atkinson, M.D., Acting Chief, Division of Rheumatology, Samuel B. Grant Professor of Clinical Medicine, Department of Medicine, Department of Molecular Biology, Washington University School of Medicine

1:40 p.m. to 2:05 p.m.          Classical      

B. Paul Morgan, M.D., Ph.D., Department of Medical Biochemistry and Immunology, School of Medicine, Cardiff University, Cardiff, United Kingdom

2:05 p.m. to 2:30 p.m.          Alternative   

Dennis Hourcade, Ph.D., Research Associate, Professor of Medicine, Washington University School of Medicine

2:30 p.m. to 2:45 p.m.          Provocateur Discussant 

Kathleen Sullivan, M.D., Ph.D., Chief, Division of Allergy and Immunology, The Children's Hospital of Philadelphia, Professor of Pediatrics, University of Pennsylvania

Session V                            “Lessons from T Cells”

2:45 p.m. to 3:10 p.m.          Introduction

Luigi Notarangelo, M.D., Director, Research and Molecular Diagnosis Program on Primary Immunodeficiencies, Children’s Hospital Boston; Professor of Pediatrics and Pathology, Harvard University

3:10 p.m. to 3:35 p.m.          DiGeorge anomaly

Mary Louise Markert,  M.D., Ph.D., Associate Professor of Pediatrics, Associate Professor of Immunology, Duke University

3:35 p.m. to 4:00 p.m.          T reg 

Ethan Shevach, M.D.,  Chief, Cellular Immunology Section, National Institute of Allergy and Infectious Diseases (NIAID)/ National Institutes of Health (NIH)

4:00 p.m. to 4:15 p.m.          Provocateur Discussant 

Nora Sarvetnick, Ph.D., Professor, University of Nebraska Medical Center, Lied Transplant Center, Nebraska Medical Center

4:15 p.m. to 4:40 p.m.          Break   

Session VI                           “Looking Forward”

4:40 p.m. to 4:55 p.m.          Introduction

C. M. Roifman, M.D., FRCP, FCACB, Division Head Immunology and Allergy, The Hospital for Sick Children, Senior Scientist, Molecular Structure & Function, Professor Pediatrics, Medicine, and Immunology, University of Toronto, Canada

4:55 p.m. to 5:25 p.m.          Gene Therapy        

Fabio Candotti, M.D., Senior Investigator, Genetics and Molecular Biology Branch, Head, Disorders of Immunity Section, National Human Genome Research Institute (NHGRI)/National Institutes of Health (NIH)

5:25 p.m. to 5:40 p.m.          NEMO           

Ashish Jain, M.D., Chief, Clinical Immunology Unit, National Institute of Allergy and Infectious Diseases (NIAID)/National Institutes of Health (NIH)

5:40 p.m. to 5:55 p.m.          Provocateur Discussant 

Yehuda Shoenfeld, M.D., FRCP, Head, Department of Medicine 'B' and Center for Autoimmune Diseases,

Sheba Medical Center, Tel Aviv, Israel

5:55 p.m. to 7:15 p.m.          Reception and Poster Presentations by Young

Investigators            

7:15 p.m.                               Dinner (on the town)

Sunday, November 15, 2009

8:00 a.m. to 9:00 a.m.          Continental Breakfast            

Session VII                          Panel Discussion: “Clinical Implications:

Autoimmunity and Immunodeficiencies”

9:00 a.m. to 10:00 a.m.        Chair: Ian R. Mackay, A.M., M.D., F.A.A, Monash

University, Australia

Panel Members: Hans Ochs, M.D. , University of Washington, John Routes, M.D., Medical College of Wisconsin, M. Eric Gershwin, M.D., University of    California-Davis

10:00 a.m. to 11:30 a.m.      Wrap-up and Synthesis   

Discussion by meeting Provocateur Discussants:

Josiah Wedgwood, Harvey W. Schroeder, Jr., Mel Berger, J. P. Atkinson, Ian R. Mackay, C. M. Roifman, Nora Sarvetnick, Kathleen Sullivan, Paolo Casali, Warren Strober, Hans Ochs, Yehuda Shoenfeld

11:30 a.m. to 12:00 p.m.      Recommendations for Future Research        

Noel R. Rose, M.D., Ph.D., Professor of Pathology, Professor of Molecular Microbiology and Immunology, Director of Johns Hopkins Center for Autoimmune Disease Research, Bloomberg School of Public Health

12:00 p.m.                             Adjournment  

Registration Information:

The colloquium is open by invitation only to medical doctors and scientific investigators.

If you are a specialist in the field of immunodeficiency and/or autoimmune diseases and would like to be considered for invitation, please forward your full name, title, and research institution affiliation to khurley@aarda.org   For general information on autoimmune diseases or AARDA contact us by phone (586-776-3900) or by email (aarda@aarda.org)

Sponsorship

Sponsorship opportunities are still available.  For information on how to become involved through sponsorship email us at khurley@aarda.org 

Call for Abstracts

For Information click here www.aarda.org/user_content/Immunodef_AbstractCall.php