Cogan syndrome is rare autoimmune-mediated rheumatic disorder characterized by recurrent cornea inflammation, fever, weight loss and hearing loss. It can lead the patient to blindness or deafness if not treated properly. In 1945 D.G. Cogan first described this term. People of 20s, 30s and children are mostly affected by Cogan syndrome.
What causes Cogan syndrome?
The exact cause of cogan syndrome is still unknown, but thought that it is an autoimmune disorder. Patients own antibody to inner ear and eye tissue causes the eye and ear inflammation. Infection with the bacteria Chlamydia pneumoniae has been demonstrated in some patients prior to the development of Cogan’s syndrome but not proved at.
What are the symptoms of cogan syndrome?
How is cogan syndrome diagnosed?
Felty’s syndrome is diagnosed by patient’s history, physical examination and lab tests.
Lab tests shows:
Cogan syndrome can occur in children, and is particularly difficult to recognize in that situation.
How to managed cogan syndrome ?
Anti-inflammatory eye and ear drops are used is mild cases. For moderate cases antibiotic drops can be used. For more severe disease, oral corticosteroids may be necessary to reduce the inflammatory response. When large amounts of steroids are required or if the disease is severe and is not responding to steroid therapy, other immunosuppressive medications like Methotrexate, cyclophosphamide, cyclosporine, and azathioprine are recommended. In some severe cases surgical repair of eye may be done .
This blog post was originally published by AutoimmuneMom.com, written by Emedicinezone.com, and first published on Jun 10, 2010.