Axonal & neuronal neuropathy (AMAN)

Axonal & neuronal neuropathy (AMAN)

Axonal & neuronal neuropathy (AMAN) is a variant of Guillain-Barré syndrome, an autoimmune disease

Axonal & neuronal neuropathy (AMAN) is a variant of Guillain-Barré syndrome, an autoimmune disease. It is characterized by acute paralysis and loss of reflexes without sensory loss. The syndrome typically presents as a progressive symmetric paralysis (loss of muscle function) with areflexia (absence of neurologic reflexes such as the knee jerk reaction), often causing respiratory failure. Antibodies attack the coating of the motor neurons without causing inflammation. It does not affect sensory neurons, so sensation remains intact despite loss of movement.

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Patricia Barber
Patricia Barber
For the last 20 years, Pat has been helping patients and caregivers live better lives, advocate for change, and Virginia's "right hand" making sure the "i's" are dotted and the "t's" are crossed. She lives in Michigan and couldn't picture herself doing anything but helping the autoimmune community.