What are the types of autoimmunity?

What are the types of autoimmunity?

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Particular autoimmune disorders are frequently classified into organ-specific disorders and non-organ-specific types. Autoimmune processes can have various results, for example, slow destruction of a specific type of cells or tissue, stimulation of an organ into excessive growth, or interference in its function. Organs and tissues frequently affected include the endocrine gland, such as thyroid, pancreas, and adrenal glands; components of the blood, such as red blood cells; and the connective tissues, skin, muscles, and joints. Some autoimmune diseases fall between the two types. Patients may experience several organ-specific diseases at the same time. There is however little overlap between the two ends of the spectrum.

In organ-specific disorders, the autoimmune process is directed mostly against one organ. Examples, with the organ affected, include Hashimoto’s thyroiditis (thyroid gland), pernicious anemia (stomach), Addison’s Disease (adrenal glands), and Type 1 Diabetes (pancreas).

In non-organ-specific disorders, autoimmune activity is widely spread throughout the body. Examples include rheumatoid arthritis, systemic lupus erythematosus (SLE or lupus), and dermatomyositis.

William Zrnchik
William Zrnchik
Will instinctively sees the fibers of opportunity woven throughout an organization, binds them into a cohesive whole, encourages others to extend their knowledge, and creates organizational advantage. He is a motivational leader who uses stories to inspire action, a champion of nonprofit leadership and development, and fosters innovation at all levels.